Cigarette cessation: is vaping effective and risk-free?

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For over 10 years, the Cochrane Institute has been conducting ongoing analyses to update its study on the effectiveness of the e-cigarette in cigarette cessation. The most recent update, published in its journal in January 2025, includes two new studies confirming that e-cigarettes used with nicotine e-liquids remain the most effective tools for quitting smoking, with no serious adverse effects.

The Cochrane Institute study

The independent, non-profit international organisation Cochrane has a mission to promote informed decision-making by healthcare professionals, researchers and caregivers. Since its creation in 1993, it has published comprehensive reviews of robust research evidence aimed at patients as well as healthcare professionals, researchers and caregivers.

The reasons for the study

The Cochrane Institute started from the observation that many people struggle to begin their cigarette cessation. The aim of the study was to verify whether the use of substitutes such as e-cigarettes could genuinely help people quit smoking. In a second phase, the study was intended to measure whether users experienced any adverse effects with this type of device.

As a reminder, e-cigarettes heat a liquid composed of flavourings and nicotine, thus allowing consumers to inhale nicotine in the form of vapour rather than smoke. Without combustion, e-cigarettes do not expose users to the same toxic chemicals as traditional cigarettes.

The study methodology

To conduct its observations, the Cochrane Institute based its work on 90 American, British and Italian studies published up to 1 February 2024 and covering 29,044 adult smokers. These various studies focused on the use of the nicotine e-cigarette in the context of cigarette cessation in comparison with: 

• Patches and nicotine gum ;
• Varenicline (medication) ;
• Nicotine-free e-cigarettes ;
• Products designed to heat tobacco ;
• Nicotine pods ;
• Behavioural support ;
• The absence of support.

The researchers focused particularly on controlled clinical trials, where the assignment of treatments to participants is randomised. Indeed, these studies are often recognised as providing the most robust data on the effects of a treatment.

The Cochrane Institute focused on:

• The number of people who stopped smoking for at least 6 months ;
• The side effects recorded after at least one week of use.

The results of the Cochrane Institute study 

According to the Cochrane Institute, the nicotine e-cigarette is today the most effective cigarette cessation tool. The study results indicate that these devices show better results than nicotine replacement therapies (NRT) for example.

More specifically, evidence has shown that nicotine e-cigarettes increased the rate of people quitting traditional tobacco products for at least 6 months compared to non-nicotine devices.

Out of 100 people using nicotine e-cigarettes to quit smoking, 8 to 10 could successfully quit completely, compared to only 6 out of 100 people using patches and nicotine gum for example, and 7 out of 100 using nicotine-free e-cigarettes.

Regarding the side effects recorded after at least one week of e-cigarette use, the study noted minor throat irritations, headaches and coughing. It is worth noting that people using patches or nicotine gum reported the same symptoms. Participants also reported that these effects tended to subside over time.

Once again, the Cochrane Institute has demonstrated that the e-cigarette is the subject of a great deal of misinformation. By studying vaping in a 100% independent manner, the organisation dispels misconceptions with robust evidence, pointing out that the nicotine e-cigarette is today a highly effective means of cigarette cessation.

And you, when will you begin your cigarette cessation?

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• Restored flavours & powerful hit: for a satisfying vaping experience that makes you forget the traditional cigarette ;
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